Research Highlights
Biology & Medicine
- Neutrons help shed light on critical protein activity that protects our DNA
Published Work: “A new structural framework for integrating replication protein A into DNA processing machinery”
Contact: Walter Chazin
- SNS researchers overcome the freezing sample problem in biostudies
(2012)
Published Work: “Water-protein dynamic coupling and new opportunities for probing it at low to physiological temperatures in aqueous solutions"
Contact: Eugene Mamontov
- Studying how a protein's dynamics can take down a killer
(2012)
Contact: Melissa Sharp - Martha "cow-laborates" to help unravel protein structure in milk
(2012)
Published Work: "Casein micelles and their internal structure”
Contact: C. G. de Kruif - Detecting the shape of polymer chains inside polyelectrolyte biomaterials
(2012)
Published Work: “A Small-Angle Neutron Scattering Study of the Equilibrium Conformation of Polyelectrolytes in Stoichiometric Saloplastic Polyelectrolyte Complexes”
Contact: Marie Markarian - SANS tracks cell death protein invading biomimetic mitochondrial membrane
(2011)
Published Work: “Interaction of the full-length BAX protein with biomimetic mitochondrial liposomes: A small-angle neutron scattering and fluorescence study”
Contact: John Katsaras - Building a Road Map for Tailoring Multilayer Films for Medicine
Published Work: "Steric Effects in Ionic Pairing and Polyelectrolyte Interdiffusion within Multilayered Films: A Neutron Reflectometry Study" (2011)
Contact: John Ankner - SANS Detects Contaminants in Insulin, Improving It as a Tool To Study Alzheimer's
Researchers measure aggregates then remove them in 2-step process. (2011)
Published Work: "Detection and reduction of microaggregates in insulin preparations"
Contact: Georges Belfort
- First-Ever Sub-Nanoscale Snapshots of Renegade Protein in Huntington's Disease
For the first time, researchers have successfully characterized the earliest structural formation of the disease type of the protein “huntingtin” that creates such havoc in Huntington’s Disease. (2011)
Published Work: "Structural Formation of Huntingtin Exon 1 Aggregates Probed by Small-Angle Neutron Scattering"
Contact: Chris Stanley
